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Leap 06

Reverse auoimmune diseases and chronic inflammation

What if?

What if we could permanently reverse the autoimmune process?

Health impacts

4% of the global population live with an autoimmune disease. Assuming that the individual burden of such diseases is 13.2% lost wellbeing annually (an average across the burdens of type 1 diabetes, rheumatoid arthritis, psoriasis, and multiple sclerosis) it can be assumed that a cure for all autoimmune diseases could save 3.99 million WALYs in Europe.




Cure all autoimmune diseases (EU)

533.27

WALY per 100.000 individuals

Community impacts

Being close to someone with an autoimmune disease can have a direct impact on one’s own quality of life, but just as autoimmune diseases vary in terms of their impact on patients, so do their effects on caregivers and family members. For both rheumatoid arthritis and diabetes, we identify significant but minor negative impacts on partners of patients. Partners of patients of rheumatoid arthritis and type 1 diabetes lose 1.8% and 1.3% of their potential wellbeing, respectively.




Cure rheumatoid arthirits (Partner burden EU)

5.31

Cure multiple sclerosis (Partner burden EU)

16.33

WALY per 100.000 individuals

Stability impacts

Being close to someone with an autoimmune disease can have a direct impact on one’s own quality of life, but just as autoimmune diseases vary in terms of their impact on patients, so do their effects on caregivers and family members. For both rheumatoid arthritis and diabetes, we identify significant but minor negative impacts on partners of patients. Partners of patients of rheumatoid arthritis and type 1 diabetes lose 1.8% and 1.3% of their potential wellbeing, respectively.




Lift economic burden of autoimmune
diseases (Europe

39.94

WALY per 100.000 individuals