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Leap 02

Provide sustainable organ & tissue replacement

What if?

What if we could stop the progression of Parkinson’s disease, or even cure it through replacement of damaged cells to restore tissue function? Or what if a diagnosis of kidney failure meant scheduling a prompt transplant operation, without having to wait for years for an organ donor? What if this operation had very low risks of organ rejection, and meant skipping dialysis entirely?

Health impacts

According to our estimations, chronic kidney disease (CKD) emerges as one the most burdensome diseases in Europe. Assuming a prevalence for stage 3-5 CKD of 11.86% in Europe, and an annual wellbeing loss to patients equal to 8.8%, ending organ shortage could be projected to save up to 2.5 million WALYs in Europe.


For Parkinson’s, we estimate that a patient may lose about 29% of the wellbeing they could have enjoyed if they never had the disease (0.29 WALY´s lost). Given the prevalence of this disease in Europe, we find that the total number of WALYs saved amount to 195,300 in Europe if this disease was cured.




Cure Chronic Kidney Disease (CKD) (Germany)

947.89

Cure Parkinson’s disease (EU)

43.86

WALY per 100.000 individuals

Community impacts

CKD and Parkinson’s are known to be particularly burdensome conditions for partners and family members of the patients, as they often require intensive care.


In our analysis, we find that both partners of patients with chronic kidney disease and Parkinson’s lose approximately 2.5% - 3% of their potential wellbeing annually (0.025 – 0.03 WALYs).




Cure CKD (Partner burden EU)

172.92

Cure Parkinson's disease (Partner burden EU)

5.08

WALY per 100.000 individuals

Stability impacts

CKD and Parkinson’s are known to be particularly burdensome conditions for partners and family members of the patients, as they often require intensive care.


In our analysis, we find that both partners of patients with chronic kidney disease and Parkinson’s lose approximately 2.5% - 3% of their potential wellbeing annually (0.025 – 0.03 WALYs).




Lift economic burden of CKD transplants
(Nordic countries)

24.94

Lift economic burden of Parkinson’s disease (UK)

6.38

WALY per 100.000 individuals